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BATTLE // -332 BCE

Battle of Issus

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Significance

The Battle of Issus was the second major engagement of Alexander the Great's invasion of the Achaemenid Empire and the first direct confrontation between Alexander and the Persian king Darius III. The Macedonian victory, achieved against a Persian force that outnumbered them by a significant margin, demonstrated that Alexander's army could defeat Darius in open battle. The flight of Darius from the field carried immediate political consequences: his family and treasury fell into Macedonian hands, stripping the Persian king of both personal authority and material resources and exposing the fragility of Achaemenid command under pressure. Within the Wars of Alexander the Great, the battle opened the way for the subsequent Macedonian advance into the Levant and Egypt, removing the threat of a large Persian field army in the west and shifting the strategic initiative firmly to Alexander.

Forces & casualties

Troop strength

  • Macedon37,000
    medium
  • Achaemenid Empire50,000–100,000
    medium

Achaemenid Empire fielded a 2.0 : 1 numerical advantage

Casualties

  • Macedon4,500
    medium12% loss rate
  • Achaemenid Empire20,000–40,000
    medium40% loss rate

Commanders (5)

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Related

6 sibling battles · 0 factions

Last verified July 2026
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